1 Dr Azizullah Langah , 2 Dr Naseer Ahmad Memon , 3Aziz ur Rahman , 4 Dr Mohammad Kamran, 5Asad Khalil , 6 Vagma Rahman,
1Associate Professor, Department of Paediatrics, Peoples University of Medical and Health Sciences for Women, Nawab shah, Sindh
2Associate Professor, Department of Paediatrics, Peoples University of Medical and Health Sciences for Women, Nawab shah, Sindh
3 Urology Department, Northwest General Hospital Peshawar
4 Anesthesia Department, NWGH
5 Dept of Medicine Lady Reading Hospital, Peshawar
6 Department of Surgery , NWGH, Peshawar
Abstract
Aim: The present study investigated the association of Early Patulous Eustachian Tube (PET) with BMI in young female patients, explored new diagnosis criteria and functionally defined clinical influence on PET as a reflective balance of lower range or variable low value directionality to link it to at least one positive threshold criterion.
Method: Data on demographics, BMI & medical history were collected from a cohort of young women with symptoms compatible with PET. PET was diagnosed by (1) tympanometry and endoscopic examination paid much attention in patient of Eustachian tube function patency as the diagnostic Standard. Correlations between PET severity scores and BMI categories as well as with established diagnostic criteria were studied using statistical analyses.
Results: The range of B M I was from underweight to normal weight with most patients falling into the category of under and or low body mass . Diagnosis was established by means of symptomatic and objective measurement tests, confirming PET without significant changes on 18F-FDG-PET temporally to BMI fluctuations in repeated evaluations. Significant associations with increasing PET severity include a lower BMI [BMI serves as an effect modifier of Eustachian tube (ET) function], as demonstrated in our statistical analyses.
Conclusion: This study illustrates the importance of BMI in determining PET severity and suggests that targeted management strategies may be required for young, female patients with lower BMIs. These discoveries add to an understanding of PET pathophysiology, aid in the accurate diagnosis and selection of patients for therapy (including timing for intervention), as well support early interventional strategies designed to reduce symptoms associated with PET prior further sequelae. Continued work is needed to determine the underlying mechanisms involved in this difficult otologic condition as well how best to personalize care for these individuals.
Keywords: Patulous Eustachian Tube , Low Body Mass Index , Autophony , Padiatric Audiology , Hormonal Imbalance.