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OCTOBER 2017 | VOL. 9, NO. 20

VOLUME 9, ISSUE 20 / OCTOBER 2017

Methodology

OCTOBER 2017

Immunoprecipitation middle-up LC–MS for in vivo drug-to-antibody ratio determination for antibody–drug conjugates
  • John A Davis
  • Mark Kagan
  • Jessica Read
  • Markus Walles & 
  • Panos Hatsis
  • Pages:1535–1549
  • Published Online:26 October 2017
Methodology

SEPTEMBER 2017

LC–MS determination of fentanyl in human serum and application to a fentanyl transdermal delivery pharmacokinetic study
  • Mingming Yu
  • Inas A Abdallah
  • Soo Hyeon Shin
  • Dana C Hammell
  • Audra L Stinchcomb & 
  • Hazem E Hassan
  • Pages:1551–1560
  • Published Online:15 September 2017
Research Article

OCTOBER 2017

Immunoaffinity LC–MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker
  • Hongwei Zhang
  • Huidong Gu
  • Petia Shipkova
  • Eugene Ciccimaro
  • Huadong Sun
  • Qihong Zhao & 
  • Timothy V Olah
  • Pages:1573–1588
  • Published Online:26 October 2017
Bioanalytical Challenge

OCTOBER 2017

Overcoming challenges associated with the bioanalysis of an ester prodrug and its active acid metabolite
  • Hermes Licea Perez
  • Dana Knecht & 
  • Maria Busz
  • Pages:1589–1601
  • Published Online:26 October 2017
Bioanalytical Challenge

OCTOBER 2017

Generation of assay positive controls for detection of isotype anti-drug antibodies for immunogenicity monitoring
  • Jinsong Yang
  • Yongchang Qiu & 
  • Luying Pan
  • Pages:1603–1615
  • Published Online:26 October 2017
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