VOLUME 11, ISSUE 21 / NOVEMBER 2019
Methodology
OCTOBER 2019
Importance of probe design for bioanalysis of oligonucleotides using hybridization-based LC-fluorescence assays
- Yuhuan Ji,
- Yijiang Liu,
- Wanhong Xia,
- Alexander Behling,
- Min Meng,
- Patrick Bennett &
- Laixin Wang
- Pages:1917–1925
- Published Online:22 October 2019
Research Article
DECEMBER 2019
LC–MS quantification of oligonucleotides in biological matrices with SPE or hybridization extraction
- Luc Sips,
- Emmanuel Njumbe Ediage,
- Benno Ingelse,
- Tom Verhaeghe &
- Lieve Dillen
- Pages:1941–1954
- Published Online:12 December 2019
Research Article
DECEMBER 2019
Discovery of a novel deaminated metabolite of a single-stranded oligonucleotide in vivo by mass spectrometry
- Jing Li,
- Ju Liu,
- Jennifer Enders,
- Michael Arciprete,
- Chris Tran,
- Krishna Aluri ,
- Li-Hua Guan,
- Jonathan O’Shea,
- Anna Bisbe,
- Klaus Charissé,
- Ivan Zlatev,
- Diana Najarian &
- Yuanxin Xu
- Pages:1955–1965
- Published Online:12 December 2019
Research Article
DECEMBER 2019
Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectrometry
- Ju Liu,
- Jing Li,
- Chris Tran,
- Krishna Aluri ,
- Xuemei Zhang,
- Valerie Clausen,
- Ivan Zlatev,
- Lihua Guan,
- Saeho Chong,
- Klaus Charisse,
- Jing-Tao Wu,
- Diana Najarian &
- Yuanxin Xu
- Pages:1967–1980
- Published Online:12 December 2019
Perspective
OCTOBER 2019
Bioanalysis of adeno-associated virus gene therapy therapeutics: regulatory expectations
- Boris Gorovits,
- Jean-Claude Marshall,
- Justin Smith,
- Laurence O Whiteley &
- Hendrik Neubert
- Pages:2011–2024
- Published Online:25 October 2019