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NOVEMBER 2018 | VOL. 10, NO. 22

VOLUME 10, ISSUE 22 / NOVEMBER 2018

Bioanalytical Challenge

OCTOBER 2018

Validation and reproducibility of an LC–MS/MS method for emixustat and its three deaminated metabolites in human plasma
  • Terry Podoll
  • Lisa Geisler
  • Michael Van Parys
  • Glenn Hanson & 
  • Michael J Reid
  • Pages:1803–1817
  • Published Online:16 October 2018
Research Article

OCTOBER 2018

Optimizing hybrid LC–MS/MS binding conditions is critical: impact of biotransformation on quantification of trastuzumab
  • Luna Liu
  • Keyang Xu
  • Jenny Li
  • Mauricio Maia
  • Mary Mathieu
  • Rebecca Elliott
  • Jihong Yang
  • Ihsan Nijem & 
  • Surinder Kaur
  • Pages:1819–1831
  • Published Online:16 October 2018
Research Article

OCTOBER 2018

Advancing the analysis of terbutaline in urine samples using novel enzyme hydrolysis
  • Florence R Wang
  • Jing Fei
  • Xiao-Lan Yu
  • Xi-Cheng Zhao
  • Qian Wang & 
  • Kalmorat Metavarayuth
  • Pages:1853–1860
  • Published Online:29 October 2018
Review

OCTOBER 2018

Review of approaches and examples for monitoring biotransformation in protein and peptide therapeutics by MS
  • John F Kellie & 
  • Molly Z Karlinsey
  • Pages:1877–1890
  • Published Online:16 October 2018
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