ABSTRACT
Background: Diabetes Mellitus (DM) and Lower Urinary Tract Symptoms (LUTS) are prevalent conditions with significant impacts on quality of life. Despite their individual burdens, the relationship between DM and LUTS remains underexplored, necessitating comprehensive investigation.
Aim: This study aimed to investigate the association between Diabetes Mellitus and Lower Urinary Tract Symptoms, encompassing prevalence rates, underlying mechanisms, and effective management strategies.
Methods: A prospective cohort study was conducted at Services Hospital from May 2023 to November 2023. A total of 100 participants were recruited, comprising individuals diagnosed with DM and those without. Data regarding LUTS, DM duration, glycemic control, urinary parameters, and relevant clinical variables were collected. Statistical analyses, including chi-square tests, t-tests, and logistic regression, were performed to assess associations and identify potential confounders.
Results: The prevalence of LUTS among individuals with DM was found to be significantly higher compared to non-diabetic counterparts (p < 0.05). Furthermore, diabetic patients exhibited a higher frequency of specific LUTS subtypes, including urinary urgency, frequency, and nocturia. Mechanistically, poor glycemic control and longer DM duration were identified as significant predictors of LUTS severity (p < 0.01). Additionally, alterations in urinary parameters, such as increased post-void residual volume, were observed among diabetic individuals with LUTS. Management strategies, including lifestyle modifications, pharmacotherapy, and diabetic control measures, were effective in alleviating LUTS burden in this population.
Conclusion: Our findings underscore a significant association between Diabetes Mellitus and Lower Urinary Tract Symptoms, highlighting the importance of proactive screening and management strategies in diabetic care. Effective glycemic control and targeted interventions may mitigate LUTS burden, thereby improving overall quality of life in individuals with DM.
Keywords: Diabetes Mellitus, Lower Urinary Tract Symptoms, prevalence, mechanisms, management strategies, glycemic control, urinary parameters, Services Hospital.