ABSTRACT
Background: Primary open-angle glaucoma (POAG) poses a significant threat to vision globally, considered by progressive optic nerve damage and visual field loss. Intravitreal injections have emerged as a potential therapeutic intervention for various ocular conditions, yet their impact on the rate of progression in POAG remains uncertain.
Aim: This research aimed to comprehensively evaluate influence of intravitreal injections on rate of progression in individuals diagnosed having primary open-angle glaucoma.
Methods: A retrospective analysis was conducted on the cohort of patients identified having POAG who received intravitreal injections as part of their treatment regimen. Clinical data including baseline characteristics, intraocular pressure (IOP) measurements, visual field-testing results, and optic nerve assessments were collected and analyzed over a specified follow-up period.
Results: Analysis of the collected data revealed trends indicative of the impact of intravitreal injections on rate of progression in primary open-angle glaucoma. Changes in visual field parameters, optic nerve morphology, and intraocular pressure dynamics were observed over the course of follow-up.
Conclusion: Intravitreal injections may exert a mitigating effect on rate of progression in primary open-angle glaucoma, as evidenced by the observed alterations in clinical parameters. Additional future studies, involving larger cohorts and extended follow-up periods, are necessary to confirm these results and clarify the underlying mechanisms.
Keywords: Primary open-angle glaucoma, intravitreal injections, progression, visual field, optic nerve, intraocular pressure.