ABSTRACT
Background: Pregnancy brings about physiological changes that can exacerbate pre-existing respiratory conditions or precipitate acute respiratory illnesses. Understanding the interplay between acute and chronic respiratory diseases during pregnancy is crucial for mitigating adverse outcomes such as spontaneous premature rupture of membranes (sPPROM).
Aim: This study aimed to investigate the relationship between acute and chronic respiratory diseases in pregnant women and their association with sPPROM.
Methods: A retrospective cohort study was conducted, involving pregnant women with documented respiratory conditions from a tertiary care hospital over a five-year period. Medical records were analyzed to identify the prevalence of acute respiratory illnesses, chronic respiratory diseases, and occurrences of sPPROM. Statistical analyses, including logistic regression, were employed to assess the association between respiratory conditions and sPPROM.
Results: Among the cohort of pregnant women, a significant proportion presented with either acute respiratory illnesses or chronic respiratory diseases. The incidence of sPPROM was notably higher in women with pre-existing chronic respiratory conditions compared to those without such conditions. Furthermore, pregnant women who experienced acute respiratory illnesses during pregnancy demonstrated an increased risk of sPPROM compared to those who did not.
Conclusion: Our findings underscore the intricate relationship between acute and chronic respiratory diseases in pregnancy and their impact on obstetric outcomes, particularly sPPROM. Early identification and management of respiratory conditions in pregnant women may help reduce the risk of adverse pregnancy outcomes.
Keywords: Pregnancy, Respiratory Diseases, Spontaneous Premature Rupture of Membranes, Acute Illness, Chronic Conditions, Obstetric Outcomes, Retrospective Cohort Study.